Publications

Check out our latest publications.

Original Publications

STEED: A data mining tool for automated extraction of experimental parameters and risk of bias items from in vivo publications.

STEED: A data mining tool for automated extraction of experimental parameters and risk of bias items from in vivo publications.
Zurrer WE, Cannon AE, Ewing E, Brüschweiler D, Bugajska J, Hild BF, Rosso M, Reich DS, Ineichen BV
PLoS One 19(11): e0311358 (2024)
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Which experimental factors govern successful animal-to-human translation in multiple sclerosis drug development? A systematic review and meta-analysis.

Which experimental factors govern successful animal-to-human translation in multiple sclerosis drug development? A systematic review and meta-analysis.
Berg I, Härvelid P, Zürrer WE, Rosso M, Reich DS, Ineichen BV
eBioMedicine 110: 105434 (2024)
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Systematic review and meta-analysis of preclinical studies.

Systematic review and meta-analysis of preclinical studies.
Ineichen BV, Held U, Salanti G, Macleod MR, Wever KE
Nature Reviews Methods Primers 4(1), 72 (2024)
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NeuroTrialNER: An Annotated Corpus for Neurological Diseases and Therapies in Clinical Trial Registries

NeuroTrialNER: An Annotated Corpus for Neurological Diseases and Therapies in Clinical Trial Registries
Doneva SE, Ellendorff TR, Sick B, Goldman JP, Cannon AE, Schneider G, Ineichen BV
EMNLP (2024) (2024)
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Analysis of animal-to-human translation shows that only 5% of animal-tested therapeutic interventions obtain regulatory approval for human applications

Analysis of animal-to-human translation shows that only 5% of animal-tested therapeutic interventions obtain regulatory approval for human applications
Ineichen BV, Furrer E, Grüninger SL, Zürrer WE, Macleod MR
PLoS Biol 22(6):e3002667 (2024)
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Myelin bilayer mapping in the human brain in vivo.

Myelin bilayer mapping in the human brain in vivo.
Baadsvik EL, Weiger M, Froidevaux R, Schildknecht CM, Ineichen BV, Pruessmann KP.
Magnetic resonance in medicine. Online ahead of print. 2024. (2024)
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Cytotoxic lesions of the corpus callosum: a systematic review.

Cytotoxic lesions of the corpus callosum: a systematic review.
Moors S, Nakhostin D, Ilchenko D, Kulcsar Z, Starkey J, Winklhofer S, Ineichen BV
European Radiology. Online ahead of print. 2023. (2023)
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The Brainbox - a tool to facilitate correlation of brain magnetic resonance imaging features to histopathology.

The Brainbox - a tool to facilitate correlation of brain magnetic resonance imaging features to histopathology.
Faigle W, Piccirelli M, Hortobágyi T, Frontzek K, Cannon AE, Zürrer WE, Granberg T, Kulcsar Z, Ludersdorfer T, Frauenknecht KBM, Reimann R, Ineichen BV
Brain Communication. 5(6): fcad307. 2023. (2023)
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Quantitative magnetic resonance mapping of the myelin bilayer reflects pathology in multiple sclerosis brain tissue.

Quantitative magnetic resonance mapping of the myelin bilayer reflects pathology in multiple sclerosis brain tissue.
Baadsvik EL, Weiger M, Froidevaux R, Faigle W, Ineichen BV*, Pruessmann KP*
Science Advances, 9(32):eadi0611. Epub 20230811. 2023. (2023)
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Virchow-Robin spaces are a marker for arterial disease in multiple sclerosis.

Virchow-Robin spaces are a marker for arterial disease in multiple sclerosis.
Ineichen BV, Cananau C, Plattén M, Ouellette R, Moridi T, Frauenknecht KBM, Okar SV, Kulcsar Z, Kockum I, Piehl F, Reich DS, Granberg T. Dilate
EBioMedicine, 92:104631. Epub 20230528. 2023. (2023)
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Neuroimaging findings in preclinical amyotrophic lateral sclerosis models-How well do they mimic the clinical phenotype? A systematic review.

Neuroimaging findings in preclinical amyotrophic lateral sclerosis models-How well do they mimic the clinical phenotype? A systematic review.
Cannon AE, Zürrer WE, Zejlon C, Kulcsar Z, Lewandowski S, Piehl F, Granberg T, Ineichen BV*
Frontiers in Veterinary Sciences, 10:1135282. Epub 20230502. 2023. (2023)
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Auto-STEED: A data mining tool for automated extraction of experimental parameters and risk of bias items from in vivo publications

Auto-STEED: A data mining tool for automated extraction of experimental parameters and risk of bias items from in vivo publications
Zürrer WE, Cannon AE, Ewing E, Brüschweiler D, Bugajska J, Hild BF, Rosso M, Reich DS, Ineichen BV
biorxiv (2023)
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The etiology and evolution of magnetic resonance imaging-visible perivascular spaces: Systematic review and meta-analysis.

The etiology and evolution of magnetic resonance imaging-visible perivascular spaces: Systematic review and meta-analysis.
Okar SV, Hu F, Shinohara RT, Beck ES, Reich DS, Ineichen BV
Frontiers in neuroscience, 17:1038011. 2023. (2023)
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Evidence for HARKing in mouse behavioural tests of anxiety

Evidence for HARKing in mouse behavioural tests of anxiety
Rosso M, Herrera A, Würbel H, Voelkl B
bioRxiv (2022) (2022)
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Handling method affects measures of anxiety, but not chronic stress in mice.

Handling method affects measures of anxiety, but not chronic stress in mice.
Novak J, Jaric I, Rosso M, Rufener R, Touma C, Würbel H
Sci Rep 12, 20938 (2022) (2022)
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The rearing environment persistently modulates mouse phenotypes from the molecular to the behavioural level

The rearing environment persistently modulates mouse phenotypes from the molecular to the behavioural level
Jaric I, Voelkl B, Clerc M, Schmid M, Novak J, Rosso M, Rufener R, Kortzfleisch V, Richter S, Buettner M, Bleich A, Amrein I, Wolfer D, Touma C, Sunagawa S, Würbel H
PLoS biology 20.10 (2022): e3001837 (2022)
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Structural magnetic resonance imaging findings and histopathological correlations in motor neuron diseases-A systematic review and meta-analysis

Structural magnetic resonance imaging findings and histopathological correlations in motor neuron diseases-A systematic review and meta-analysis
Zejlon C, Nakhostin D, Winklhofer S, Pangalu A, Kulcsar Z, Lewandowski S, Finnsson J, Piehl F, Ingre C, Granberg T*, Ineichen BV*
Frontiers in Neurology, 13:947347. Epub 20220830. 2022. (2022)
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Do multiple experimenters improve the reproducibility of animal studies?

Do multiple experimenters improve the reproducibility of animal studies?
Kortzfleisch V, Ambrée O, Karp N, Meyer N, Novak J, Palme R, Rosso M, Touma C, Würbel H, Kaiser S, Sachser N, Richter S
PLoS biology, 20(5), e3001564 (2022) (2022)
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Leptomeningeal enhancement in multiple sclerosis and other neurological diseases: A systematic review and Meta-Analysis.

Leptomeningeal enhancement in multiple sclerosis and other neurological diseases: A systematic review and Meta-Analysis.
Ineichen BV*, Tsagkas C*, Absinta M, Reich DS
NeuroImage Clinical, 33:102939. Epub 20220110. 2022. (2022)
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Neuroimaging phenotypes of CSF1R-related leukoencephalopathy: Systematic review, meta-analysis, and imaging recommendations.

Neuroimaging phenotypes of CSF1R-related leukoencephalopathy: Systematic review, meta-analysis, and imaging recommendations.
Mickeviciute GC, Valiuskyte M, Plattén M, Wszolek ZK, Andersen O, Danylaité Karrenbauer V, Ineichen BV*, Granberg T*
Journal of internal medicine, 291(3):269-82. Epub 20211222. 2022. (2022)
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Neurological manifestations of coronavirus infections - a systematic review.

Neurological manifestations of coronavirus infections - a systematic review.
Almqvist J, Granberg T, Tzortzakakis A, Klironomos S, Kollia E, Öhberg C, Martin R, Piehl F, Ouellette R, Ineichen BV
Annals of clinical and translational neurology, 7(10):2057-71. Epub 20200827. 2020. (2020)
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Magnetic resonance imaging in multiple sclerosis animal models: A systematic review, meta-analysis, and white paper.

Magnetic resonance imaging in multiple sclerosis animal models: A systematic review, meta-analysis, and white paper.
Ineichen BV, Sati P, Granberg T, Absinta M, Lee NJ, Lefeuvre JA, Reich DS
NeuroImage Clinical, 28:102371. Epub 20200802. 2020. (2020)
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Effects of weaning age and housing conditions on phenotypic differences in mice

Effects of weaning age and housing conditions on phenotypic differences in mice
Bailoo J, Voelkl B, Varholick J, Novak J, Murphy E, Rosso M, Palme R, Würbel H
Scientific reports 10.1 (2020): 11684 (2020)
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Enlarged perivascular spaces in multiple sclerosis on magnetic resonance imaging: a systematic review and meta-analysis.

Enlarged perivascular spaces in multiple sclerosis on magnetic resonance imaging: a systematic review and meta-analysis.
Granberg T, Moridi T, Brand JS, Neumann S, Hlavica M, Piehl F, Ineichen BV
Journal of neurology, 267(11):3199-212. Epub 20200613. 2020. (2020)
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Remyelination promoting therapies in multiple sclerosis animal models: a systematic review and meta-analysis.

Remyelination promoting therapies in multiple sclerosis animal models: a systematic review and meta-analysis.
Hooijmans CR, Hlavica M, Schuler FAF, Good N, Good A, Baumgartner L, Galeno G, Schneider MP, Jung T, de Vries R, Ineichen BV
Scientific reports, 9(1):822. Epub 20190129. 2019. (2019)
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Reviews

Quality, topics, and demographic trends of animal systematic reviews - an umbrella review.

Quality, topics, and demographic trends of animal systematic reviews - an umbrella review.
Hild BF, Brüschweiler D, Hild STK, Bugajska J, von Wyl V, Rosso M, Wever KE, Furrer E, Ineichen BV
J Transl Med 23(1): 21 (2025)
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Large language models to process, analyze, and synthesize biomedical texts: a scoping review

Large language models to process, analyze, and synthesize biomedical texts: a scoping review
Doneva SE, Qin S, Sick B, Ellendorff TR, Goldman JP, Schneider G, Ineichen BV
Discover Artificial Intelligence (2024)
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Misdiagnosis and underdiagnosis of multiple sclerosis: A systematic review and meta-analysis.

Misdiagnosis and underdiagnosis of multiple sclerosis: A systematic review and meta-analysis.
Zürrer WE, Cannon AE, Ilchenko D, Gaitán MI, Granberg T, Piehl F, Solomon AJ, Ineichen BV
Mult Scler 30(11-12): 1409-1422 (2024)
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Summer school for systematic reviews of animal studies: Fostering evidence-based and rigorous animal research.

Summer school for systematic reviews of animal studies: Fostering evidence-based and rigorous animal research.
Rosso M, Doneva SE, Howells DW, Leenaars CH, Ineichen BV
ALTEX, 41(1):131-134. 2024. (2024)
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From data deluge to publomics: How AI can transform animal research.

From data deluge to publomics: How AI can transform animal research.
Ineichen BV, Rosso M, Macleod MR
Lab Animal (NY), 52(10):213-214. 2023. (2023)
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Perivascular spaces and their role in neuroinflammation.

Perivascular spaces and their role in neuroinflammation.
Ineichen BV, Okar SV, Proulx ST, Engelhardt B, Lassmann H, Reich DS
Neuron,110(21):3566-81. 2022. (2022)
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Reliability of common mouse behavioural tests of anxiety: A systematic review and meta-analysis on the effects of anxiolytics

Reliability of common mouse behavioural tests of anxiety: A systematic review and meta-analysis on the effects of anxiolytics
Rosso M, Wirz R, Loretan A, Sutter N, Cunha C, Jaric I, Würbel H, Voelkl B
Neuroscience & Biobehavioral Reviews 143 (2022): 104928. (2022)
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New Prospects for Ultra-High-Field Magnetic Resonance Imaging in Multiple Sclerosis

New Prospects for Ultra-High-Field Magnetic Resonance Imaging in Multiple Sclerosis
Ineichen BV, Beck ES, Piccirelli M, Reich DS
Investigative Radiology, 56(11):773-84. 2021. (2021)
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Rituximab treatment for multiple sclerosis.

Rituximab treatment for multiple sclerosis.
Ineichen BV, Moridi T, Granberg T, Piehl F
Multiple sclerosis, 26(2):137-52. 2020. (2020)
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